Abstract : Aim and Objective: 1) To compare the blood lipid profile between cancer patients and healthy individuals. 2) To determine if the lipid profile of the serum changes throughout the pathogenesis of cancer. 3) These changed blood lipid levels can be employed as biochemical indicators of cancer situations. Introduction: As important constituents of cell membrane, lipids are crucial for maintaining the integrity of the cell. Alterations in lipid profiles have been associated to cancer because malignancy causes newly multiplying tumor cells to need more lipids for their synthesis, which depletes the body's current resources. It has been demonstrated that cancer patients exhibit hypocholesterolemia. Consequently, the reduced plasma lipid status may serve as a valuable marker to identify the early alterations in the neoplastic process.